Sarah C. Rozinek



Name: Sarah C. Rozinek
Agency: 711th Human Performance Wing/Human Effectiveness Directorate
Division: Bioeffects Division, Fort Sam Houston, TX
School: University of Texas at San Antonio
Program of Study: Ph.D., Physics
Synopsis:My work applies to photodynamic cancer therapy, solar cells, and possibly the ability to modify proteins to impart new functions. With an array of optical spectroscopy techniques and computational simulations, I explore: 1) the conformational effects of binding porphyrins (light sensitive molecules) to the protein albumin, under various pH conditions and 2) the bound systems’ response to laser irradiation. The next stage will involve specific cancer cell receptors in place of albumin.
Publications:
Sarah C. Rozinek and Lorenzo Brancaleon. "Photoinduced conformational changes of human serum albumin bound to protoporphyrin IX and hemin", Proc. SPIE 8579, Optical Interactions with Tissue and Cells XXIV, 85790G (February 15, 2013); doi:10.1117/12.2004325

Sarah C. Rozinek ; Robert J. Thomas and Lorenzo Brancaleon " Photoinduced structural changes to protein kinase A ", Proc. SPIE 8941, Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications, 89410T (March 13, 2014); doi:10.1117/12.2038561
Dates: Start: 07/2012 End: 12/2016